Minggu, 21 Februari 2010

Anti - retrovirals could halt Aids spread in five years


Anti-retroviral clinic in Kwa Zulu Natal, South Africa, 2008
South Africa has the world's highest incidence of HIV/Aids

Anti-retroviral treatments (ARVs) could stop the spread of Aids in South Africa within five years, say scientists.

Dr Brian Williams said that by providing HIV positive patients with these drugs could stop the spread at a cost of around $2-3 billion per year.

The drugs reduce the amount of virus patients have in their body fluids.

Dr Williams called for this approach at the annual meeting of the American Association for the Advancement of Science (AAAS) in San Diego.

Dr Williams, a leading figure in the field of HIV research, is based at the South African Centre for Epidemiological Modelling and Analysis (Sacema) in Stellenbosch.

He said the scale of the problem in South Africa was "enormous".

Success story

He added: "We have 30 million people infected with HIV and two million people dying each year."

We could break the back of the epidemic
Dr Brian Williams, Sacema

"The tragedy is that the disease continues unabated. The only real success story is the development of these extremely effective drugs that keep people alive and reduce their viral load by up to 2000 times. They become close to non-infectious.

"We should be looking at using the drugs to reduce transmission."

He said that if clinical trials started now, all of the HIV positive people in South Africa could be on ARV treatment within five years.

This approach, he stressed, should be complementary to the search for an Aids vaccine. An effective vaccine, he said, was still a long way away.

Dr Williams commented: "Even with a vaccine, in South Africa we would still have all of these people who are already infected - so what do we do for them?"

Kenneth Mayer, professor of medicine at Brown University in the US state of Rhone Island, agreed that treating patients early with ARVs was a matter of "public health".

Dr Williams said a few clinical trials were already beginning in North America and in Africa.

The US National Institute of Allergy and Infectious Diseases is planning a trial in New York and Washington - in districts that have an HIV positive population at a similar level to African epidemics.

"We need to get answers [from these trials] quickly. That will help us move forward," he stressed.

"We could break the back of the epidemic. If we can do it, I'm confident it will work."


Source : bbc.co.uk

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